Three indexes have been compiled: authors of main articles (including our special departments such as ‘Projects in progress’ and ‘Notes and discussions’); essay reviews; and book reviews. Co-author...

This text is a bilingual Arabic-English translation of one of the most important metaphysical works of the Persian Muslim philosopher known as Mulla Sadra & Sadr al-Din Muhammad al-Shirazi. In this work Mulla Sadra develops an anti-Platonic philosophical position which is non-Aristotelian. He holds that "existents" are ontologically prior to "essence" & that there are two different realms -- the mind dependent domain & entities which exist independent of the mind. Mulla Sadra's views became very popular among Iranian Muslim philosophers (...) & eventually were instrumental in destroying the Aristotelian school of thought in the Islamic world. The translator, Dr. Parviz Morewedge, is the Secretary-Treasurer of the Society for the Study of Islamic Philosophy & Science & has published ten books & numerous articles in Islamic Philosophy & Mysticism. (shrink)

The New Economic Windows Series, derived from Massimo Salzano's ideas and work, incorporates material from textbooks, monographs and conference proceedings that deals with both the theoretical and applied aspects of various sub-disciplines ...

Study on Islamic ethics in view of Islamic teachings.

The U.S. Food and Drug Administration's rationale for supporting the development and approval of BiDil for heart failure specifically in black patients was based on under-powered, post hoc subgroup analyses of two relatively old trials , which were further complicated by substantial covariate imbalances between racial groups. Indeed, the only statistically significant difference observed between black and white patients was found without any adjustment for potential confounders in samples that were unlikely to have been adequately randomized. Meanwhile, because the accepted (...) baseline therapy for heart failure has substantially improved since these trials took place, their results cannot be combined with data from the more recent trial amongst black patients alone. There is therefore little scientific evidence to support the approval of BiDil only for use in black patients, and the FDA's rationale fails to consider the ethical consequences of recognizing racial categories as valid markers of innate biological difference, and permitting the development of group-specific therapies that are subject to commercial incentives rather than scientific evidence or therapeutic imperatives. This paper reviews the limitations in the scientific evidence used to support the approval of BiDil only for use in black patients; calls for further analysis of the V-HeFT I and II data which might clarify whether responses to H-I vary by race; and evaluates the consequences of commercial incentives to develop racialized medicines. We recommend that the FDA revise the procedures they use to examine applications for race-based therapies to ensure that these are based on robust scientific claims and do not undermine the aims of the 1992 Revitalization Act. (shrink)

Background U.S. federal regulations require that certain ethical elements be followed to protect human research subjects. The location and clinical circumstances of a proposed research study can differ substantially and can have significant implications for these ethical considerations. Both the location and clinical circumstances are particularly relevant for research in intensive care units (ICUs), where patients are often unable to provide informed consent to participate in a proposed research intervention. Purpose Our goal is to elaborate on the updated 2013 U.S. (...) Food and Drug Administration (FDA) guidance document regarding an exemption from the requirement of obtaining informed consent from patients or their surrogates and to address certain elements within that document, thereby assisting clinicians in developing a framework for emergency research in accordance with the regulatory bodies at their own institutions and in the United States. Methods Review of the 2011 and updated FDA guidance document on exemption from informed consent. Results The current process of obtaining informed consent within ICUs needs to be revisited, especially for research in which timely informed consent is not likely. In particular, the process of obtaining informed consent may not be appropriate or even ethical for critically ill patients in extremis who require an intervention for which there is no current acceptable standard of care and clinical equipoise exists. We provide clinicians with a viewpoint that further elaborates on the FDA guidance document. Limitations The viewpoints provided herein are those of the authors and are therefore inherently limited by the personal views of a selected few. Other clinicians or researchers may not interpret the FDA guidelines in a similar manner. Moreover, the discussion of a guideline document is a limitation in and of itself. The guidelines set forth by the FDA are precisely that—guidelines. Therefore, they may not be followed as outlined in the guidance document within one’s own institution. Our goal is that, by elaborating on the guidelines for planned research involving human subjects in the ICU, institutional regulatory bodies may gain a better understanding in drafting their own document when faced with a clinician or a researcher who wishes to conduct planned research in an ICU. Conclusions We believe that the interpretations provided will allow clinicians to safely undertake planned research in ICUs without endangering the main tenets of ethical research involving human participants. This research is needed for the advancement of care in the critically ill. (shrink)

Tales of good deeds in the light of Hadith.

Drawing on a landscape analysis of existing data-sharing initiatives, in-depth interviews with expert stakeholders, and public deliberations with community advisory panels across the U.S., we describe features of the evolving medical information commons. We identify participant-centricity and trustworthiness as the most important features of an MIC and discuss the implications for those seeking to create a sustainable, useful, and widely available collection of linked resources for research and other purposes.

Darstellung des Noema in 12 Thesen.\nverwendete Textstellen: Ideen 1: S. 203, 22-23; S. 204, 20-21; S. 357, 19-20: Handlungen sind zielgerichtet. Dabei bedarf eines keines physischen Objekts. Husserl setzt and diese Stelle das Noema. Somit wird auch zielgerichtetes Handeln aufgrund einer Halluzination m{ö}glich, Zielgerichtet zu sein bedeutet ein Noema zu haben.\n1. Follesdal´sche These: Noema ist eine intensionale Entit{ä}t, eine Generalisierung des Begriffs Sinn/Bedeutung.\n2. These: Das Noema hat zwei Bestandteile, a) der noematische Sinn, der allen thetischen Handlungen (erinnern, sich vorstellen usw.) (...) gem{ä}{ß} desselben Objekts mit denselben Eigenschaften in derselben Gerichtetheit gemeinsam ist und b) die Gegebenheitsweise (hat auch Sinncharakter), die sich unterscheidet in Handlungen mit verschiedenem thetischen Charakter.\n3. These: Der noematische Sinn ergibt sich aus der Art und Weise, wie Bewu{ß}tsein zum Objekt in Relation steht.\n!! 4. These: Das Noema einer Handlung ist nicht das Objekt dieser Handlung\n5. These: Das Objekt einer Handlung ist eine Funktion des noematischen Sinns, d.h. mit einem bestimmten Noema kann nur ein Objekt korrespondieren.\n6. These: Jedoch k{ö}nnen mit einem bestimmten Objekt verschiedene Noemata korrespondieren. (z.B. kann ein Objekt das Ziel verschiedener thetischer Handlunge sein, etwa erinnern, wahrnehmen, daher:)\n6. These a): Mit einem bestimmten Objekt korrespondieren verschiedene noematische Sinne.\n7. These: Jede Handlung besteht aus nur einem Noema. Sie wird durch dieses Noema charakterisiert. (Umgekehrt trifft dies nicht zu.)\n8. These: Noemata sind abstrakte Entit{ä}ten. (Sinne sind nicht real. Sie sind bezogen auf Handlungen in tempor{ä}ren Intervallen.)\n9. These: Noemata werden nicht durch unsere Sinnesorgane wahrgenommen.\n10. These: Noemata gelangen durch ph{ä}nomenologische Reflektion ins Bewu{ß}tsein.\n11. These: Eine ph{ä}nomenologische Reflektion kann iterativ geschehen (ann{ä}herungsweise; in Schritte gegliedert). Dies ist so, weil schon die Korrespondenz zwischen Sinn und Objekt wieder ein Objekt ergibt. Es folgt ein unendlicher Regress.\nPhysische Objekte sind transzendent in dem Sinne, dass sie unendlich viele Noemata haben. Sinn kann sie nie ersch{ö}pfend erfassen.\nNoemata k{ö}nnen andererseits ein physisches Objekt repr{ä}sentieren in der Form, dass mehr intendiert wird als gesehen wird. So denkt man sich etwa bei einem Stuhl, von dem man nur zwei Beine sieht, die beiden {ü}brigen hinzu.\n12. These: Diese Muster der Vorherbestimmung bilden zusammen mit den Gegebenheitsweisen das Noema (s. These 2). (shrink)

On the controversial questions between al-Rāzī and al-Ṭūsī, Islamic philosophy; Islamic history to 1800; dissertation.

Contributions in the concept of the divine; influence; Islamic philosophy.

U.S. Department of Health and Human Services (HHS) federal regulations pertaining to the protection of human subjects at Title 45 of the Code of Federal Regulations, Part 46, Subpart A (“the Common Rule”), refer to the need for special precautions when persons characterized as vulnerable are used as human research subjects. Under the Common Rule, persons considered “vulnerablae” are those who are likely to be susceptible to coercive or undue influence; the term “vulnerable” includes “children, prisoners, pregnant women, mentally disabled (...) persons,” or those who are “economically or educationally disadvantaged.” The need for special precautions with some of these vulnerable persons in the context of research has long been addressed by both mandatory additional protections found in Subparts B through D of 45 C.F.R. pt. 46 (that arenot, coincidentally, part of the Common Rule) and additional detailed guidance documents provided by HHS or its components to investigators and their respective institutions. (shrink)

Strong Turing Determinacy, or ${\mathrm {sTD}}$, is the statement that for every set A of reals, if $\forall x\exists y\geq _T x (y\in A)$, then there is a pointed set $P\subseteq A$. We prove the following consequences of Turing Determinacy ( ${\mathrm {TD}}$ ) and ${\mathrm {sTD}}$ over ${\mathrm {ZF}}$ —the Zermelo–Fraenkel axiomatic set theory without the Axiom of Choice: (1) ${\mathrm {ZF}}+{\mathrm {TD}}$ implies $\mathrm {wDC}_{\mathbb {R}}$ —a weaker version of $\mathrm {DC}_{\mathbb {R}}$.(2) ${\mathrm {ZF}}+{\mathrm {sTD}}$ implies that every (...) set of reals is measurable and has Baire property.(3) ${\mathrm {ZF}}+{\mathrm {sTD}}$ implies that every uncountable set of reals has a perfect subset.(4) ${\mathrm {ZF}}+{\mathrm {sTD}}$ implies that for every set of reals A and every $\epsilon>0$ :(a)There is a closed set $F\subseteq A$ such that $\mathrm {Dim_H}(F)\geq \mathrm {Dim_H}(A)-\epsilon $, where $\mathrm {Dim_H}$ is the Hausdorff dimension.(b)There is a closed set $F\subseteq A$ such that $\mathrm {Dim_P}(F)\geq \mathrm {Dim_P}(A)-\epsilon $, where $\mathrm {Dim_P}$ is the packing dimension. (shrink)

Islam; doctrines; Islamic ethics; Islamic preaching.

This volume explores whether the concept of the common good might be retrieved and become central in contemporary religious social thought. Contributors include: Charles C. West, John J. Collins, Ralph McInerny; J. Philip Wogaman, Charles E. Curran, Richard John Neuhaus, Dennis P. McCann, Ernest Bartell, Michael Novak, Charles K. Wilber, John W. Cooper, Gar Alperovitz, Richard T. DeGeorge, Gerald Cavanagh, William J. Cunningham, Peter Mann, Bette Jean Bullert and David Vogel. Co-published with the Notre Dame Center for Ethics and Religious (...) Values in Business. (shrink)

V nastoi︠a︡shchem izdanii raskryvaetsi︠a︡ biografii︠a︡, a takzhe publikuetsi︠a︡ znachitelʹnai︠a︡ chastʹ ėpistoli︠a︡rnogo nasledii︠a︡ poluzabytogo filosofa Adolʹfa Markovicha Lazareva (1872-1944), odnogo iz blizhaĭshikh druzeĭ, edinomyshlennika i uchenika Lʹva Shestova, istolkovateli︠a︡ ego filosofskikh ideĭ. V knigu vkli︠u︡cheny takzhe statʹi A. Lazareva o L. Shestove -- kak opublikovannye, tak i neizvestnye, sokhranivshiesi︠a︡ v ego arkhive. Prinadlezha k t.n. "shestovskomu" krugu -- k chislu tekh, dli︠a︡ kogo byla blizka i nesomnenna, govori︠a︡ ego sobstvennymi slovami, "volnui︠u︡shchai︠a︡ ubeditelʹnostʹ" mysli velikogo filosofa, A. Lazarev okazalsi︠a︡ fakticheski vne issledovatelʹskogo (...) i chitatelʹskogo vnimanii︠a︡. Dannai︠a︡ kniga i︠a︡vli︠a︡etsi︠a︡, po sushchestvu, pervym opytom privlechʹ interes k ego lichnosti i trudam. (shrink)

Emotion evaluations are assumed to play a crucial role in the emotion regulation process. We tested a postulate from our framework of emotion dysregulation (Nowak, U., Wittkamp, M. F., Clamor, A., & Lincoln, T. M. [2021]. Using the Ball-in-Bowl metaphor to outline an integrative framework for understanding dysregulated emotion. Frontiers in Psychiatry, 12, 118), namely that the extent to which individuals evaluate an emotion as harmful and their personal resources to modify and accept/tolerate the emotion as sufficient predict the subsequent (...) use of regulation strategies. Participants (n = 118) from a community sample took part in an experience-sampling assessment over 7 days including 10 daily paired measurements. The first measured momentary affective valence and arousal along with harmfulness evaluations and evaluations of personal resources to modify and accept/tolerate an emotion. The second followed three minutes later and measured emotion regulation strategies. The more harmful individuals evaluated an emotion, the more likely they were to use an emotion regulation strategy. The more harmful individuals evaluated an emotion, and the less sufficient they evaluated their personal resources to accept/tolerate an emotion, the more likely they were to use a maladaptive emotion regulation strategy. We conclude that emotions that people evaluate as harmful or difficult to accept are most likely to be regulated in a maladaptive manner. This implies that modifying beliefs about emotions could represent a promising treatment approach. (shrink)

Wie können wir uns in der Welt ohne Selbstverlust orientieren, wie unsere rationalen Fähigkeiten und Vermögen erhalten? Kant ist der Philosoph der reinen Vernunft und des kategorischen Imperativs. Aber mit seinen Überlegungen zur Selbsterhaltung der Vernunft erweist er sich zugleich als ein Philosoph mit einem klaren Bewusstsein davon, worauf es in unserem Leben ankommt: auf Selbstbilligung und Selbstständigkeit, auf Selbstdenken und Kritik, auf Aufklärung und Humanität, auf Recht und Freiheit, auf die Überwindung unserer Unmündigkeit und auf den Austausch von Argumenten (...) und Perspektiven. Mit seinem Fokus auf die Selbsterhaltung der Vernunft bietet das Buch einen neuen Zugang zu Kants Werk und leistet zugleich einen Beitrag zur Debatte über die Modernität seines Denkens. (shrink)